论近年来畜禽疫病的特点及其预防对策

随着畜牧业的快速发展,大规模、高密度、集约化的饲养和频繁的调运等,使畜禽更易发生流行性、群发性的疫病.畜禽疫病造成的损失影响了人类的生活需要,而且某些人畜共患的疫病还给人类健康带来了严重的威胁.要保证畜牧业可持续发展和保护人类健康,控制畜禽疫病就是关健措施.由于近年畜禽疫病的变化,我们的防治对策应发生相应变化.     

Prenatal diagnosis of congenital Chagas' disease (American trypanosomiasis)

The prenatal diagnosis of congenital transmission of Chagas' disease in a pregnant woman with the indeterminate form of the disease is reported. Sonography revealed fetal hydrops at 31 weeks' gestation. Anti-Trypanosoma cruzi IgM and IgG antibodies were negative in the fetal blood sampled by cordocentesis, but T. cruzi trypomastigotes were found in its buffy coat. Owing to anemia, in utero exchange transfusion was undertaken, but fetal demise ensued. Labor was induced and a stillborn infant weighing 2030 g was delivered. The pathological examination revealed placentitis and meningoencephalitis, myocarditis and splenitis in the stillborn fetus. Amastigotes were found in the myocardium, brain and placenta. Copyright © 2004 John Wiley & Sons, Ltd.     

人群的自然和社会属性分类下PM2.5对心血管疾病的影响

为了研究人群在自然属性和社会属性分类下的效应修饰作用,利用2005~2011年北京市大气PM_2.5日均浓度、气象要素及循环系统疾病每日死亡人数数据,根据不同年龄、性别及学历将人群分组,采用时间序列的半参数广义相加模型（GAM）,定量评价大气PM_2.5对居民循环系统疾病死亡人数的影响.单污染物模型和多污染物模型结果表明,PM_2.5为影响循环系统疾病每日死亡人数的主要大气污染物.北京市空气中PM_2.5的浓度每增加10μg/m³,循环系统疾病总死亡人数增加0.50%（95% CI：0.36,0.63）.不同人群的易感程度不同,各人群死亡人数的增加范围为0.23~0.71%,女性、60~74岁人群、文盲人群的健康风险相对较高.在文盲人群中,老年（60+）女性占比为66.2%,为了分离社会属性人群分类中可能存在的自然属性因素干扰,本文去除其中老年、女性这两个混杂因素的影响,文盲人群健康风险仍然大于较高学历的人群.年龄和性别因素叠加在学历因素上,可能加大低学历人群的健康风险,对于这部分叠加了自然因素和社会因素双重敏感性的人群应给与重点关注.     

Diagnosis of cardiac defects: where we've been,where we are and where we're going

There has been tremendous development in the field of prenatal diagnosis of cardiac disease in the last 30 years. Early work centered on the technical aspects of providing an accurate assessment of cardiac structure and function. Techniques of fetal cardiac screening have been developed and utilized throughout the world. More recently, investigators have begun to explore the ramifications of fetal cardiac diagnosis by assessing measures of outcome. In this article, the field of fetal echocardiography, as a screening tool for identifying congenital heart disease, and its impact on disease outcome is reviewed. Copyright © 2002 John Wiley & Sons, Ltd.     

Environmental change,development and vectorborne disease: Malaysia’s experience with filariasis,scrub typhus and dengue

During Malaysia’s rapid economic development into becoming a middle income country in the past several decades, environmental changes resulted in altered land use patterns because of agricultural practices such as large scale rice, rubber and oil palm cultivation. The impact of environmental changes brought about by rice and rubber cultivation affected the breeding habitats of mosquito vectors which in turn affected the prevalence of two strains of lymphatic filariasis in different ways. With scrub typhus, the development of oil palm plantations affected the ecology of mite and rodent populations which resulted in very high incidence of the disease in affected populations. Malaysia’s relentless urbanization has resulted in increased incidence of dengue, as peridomestic mosquito vectors increasingly colonize urban habitats. This article discusses how ecological factors determine the way lymphatic filariasis, scrub typhus and dengue were spread in Malaysia. The nation’s experience with environmental changes due to rapid development provides lessons for other developing countries in control programs and public health policy.